Description

6-Bromo-2-Phenylquinoline-4-Carbonyl Chloride is a high-value, reactive chemical intermediate primarily used in advanced organic synthesis. This compound matters for its role as a key building block in the development of complex molecules, particularly in pharmaceutical research and material science. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require a reliable and high-purity precursor for constructing quinoline-based scaffolds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds with quinoline cores.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that leverage the biological activity of halogenated quinolines.
• Material Science: Serves as a building block for creating organic light-emitting diodes (OLEDs), liquid crystals, and other advanced functional materials.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as an acylating agent due to the reactive carbonyl chloride group.
• Academic & R&D: A valuable reagent for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and industrial laboratories.

Basic Information

Product Name	6-Bromo-2-Phenylquinoline-4-Carbonyl Chloride
CAS No.	1160253-29-1
Molecular Formula	C₁₇H₉BrClNO
Molecular Weight	358.62 g/mol
Synonyms	6-Bromo-2-phenylquinoline-4-carbonyl chloride; 2-Phenyl-6-bromoquinoline-4-carbonyl chloride; 6-Bromo-2-phenyl-4-quinolinecarbonyl chloride; Quinoline-4-carbonyl chloride, 6-bromo-2-phenyl-; 1160253-29-1
EINECS	Contact for details

Quality Control

Our 6-Bromo-2-Phenylquinoline-4-Carbonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.