Description

6-Bromo-2-(2-Ethoxyphenyl)Quinoline-4-Carbonyl Chloride is a high-purity, advanced pharmaceutical intermediate characterized by its reactive carbonyl chloride functional group. This compound is of significant commercial value for its role as a key building block in the synthesis of complex, biologically active molecules. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel quinoline-based drug candidates, including potential kinase inhibitors and anticancer agents.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the construction of targeted compound libraries.
• Chemical Synthesis: Used in amide coupling reactions to introduce the quinoline moiety into more complex molecular architectures.
• Agrochemical Development: Potential intermediate for creating new active ingredients in crop protection products.
• Material Science Research: Investigated as a building block for organic electronic materials and functional dyes due to its conjugated quinoline structure.

Basic Information

Product Name	6-Bromo-2-(2-Ethoxyphenyl)Quinoline-4-Carbonyl Chloride
CAS No.	1160253-09-7
Molecular Formula	C19H13BrClNO2
Molecular Weight	402.67 g/mol
Synonyms	6-Bromo-2-(2-ethoxyphenyl)quinoline-4-carbonyl chloride; 2-(2-Ethoxyphenyl)-6-bromoquinoline-4-carbonyl chloride; 4-Quinolinecarbonyl chloride, 6-bromo-2-(2-ethoxyphenyl)-; 6-Bromo-2-(2-ethoxyphenyl)-4-quinolinecarbonyl chloride
EINECS	Contact for details

Quality Control

Our 6-Bromo-2-(2-Ethoxyphenyl)Quinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.