Description

Spiro[Cyclohexane-1,3'-Indoline]-5'-Carboxylicacid CAS NO 1160247-98-2 is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic molecular architecture. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with potential therapeutic applications. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities.
• Organic Synthesis Building Block: Employed in the construction of complex spirocyclic and heterocyclic frameworks due to its rigid, three-dimensional structure.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for methodological development and exploring new synthetic pathways.

Basic Information

Product Name	Spiro[Cyclohexane-1,3'-Indoline]-5'-Carboxylicacid
CAS No.	1160247-98-2
Molecular Formula	C15H17NO2
Molecular Weight	243.30 g/mol
Synonyms	5'-Carboxyspiro[cyclohexane-1,3'-indoline]; 1'H-Spiro[cyclohexane-1,3'-indole]-5'-carboxylic acid; Spiro[cyclohexane-1,3'-indoline]-5'-carboxylic acid; 1160247-98-2; 5'-Carboxyspiro[cyclohexane-1,3'-indoline]; 1'H-Spiro[cyclohexane-1,3'-indole]-5'-carboxylic acid; Spiro[cyclohexane-1,3'-indole]-5'-carboxylic acid
EINECS	Contact for details

Quality Control

Our Spiro[Cyclohexane-1,3'-Indoline]-5'-Carboxylicacid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.