Description

2,3-Dihydro-1H-Isoindole-4-Carbonitrile is a versatile and high-value heterocyclic building block in organic synthesis. This compound matters as a critical intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and advanced materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its heterocyclic core for biological activity.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic semiconductors, dyes, and photoresponsive materials due to its electron-deficient nitrile group and fused ring system.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and inhibitors for studying enzyme function and cellular pathways.

Basic Information

Product Name	2,3-Dihydro-1H-Isoindole-4-Carbonitrile
CAS No.	1159883-00-7
Molecular Formula	C9H8N2
Molecular Weight	144.18 g/mol
Synonyms	4-Cyano-2,3-dihydro-1H-isoindole; 1H-Isoindole-4-carbonitrile, 2,3-dihydro-; 2,3-Dihydroisoindole-4-carbonitrile; 4-CN-DHI; Isoindoline-4-carbonitrile; 4-Cyanoisoindoline
EINECS	Contact for details

Quality Control

Our 2,3-Dihydro-1H-Isoindole-4-Carbonitrile is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.