Description

3-n-Cbz-Aminomethylaniline Hcl is a protected aniline derivative, specifically an N-Carbobenzyloxy (Cbz) protected aminomethylaniline hydrochloride salt. This compound serves as a crucial pharmaceutical intermediate and building block in organic synthesis, enabling the controlled introduction of aniline functionalities. It is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development of active pharmaceutical ingredients (APIs) and complex organic molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used in the preparation of peptide analogs and mimetics where a protected aniline moiety is required.
• Agrochemical Synthesis: Intermediate in the development of advanced herbicides, fungicides, and pesticides.
• Material Science Research: Building block for creating specialized polymers and advanced organic materials.
• Dye and Pigment Manufacturing: Intermediate in the synthesis of complex aromatic dyes and colorants.
• Academic & Contract Research: Essential reagent for methodological development and synthetic chemistry research in laboratories.

Basic Information

Product Name	3-n-Cbz-Aminomethylaniline Hcl
CAS No.	1159826-16-0
Molecular Formula	C15H17ClN2O2
Molecular Weight	292.76 g/mol
Synonyms	3-(((Benzyloxy)carbonyl)amino)methyl)aniline hydrochloride; 3-(Aminomethyl)-N-(benzyloxycarbonyl)aniline hydrochloride; 1-(3-Aminobenzyl)-3-(benzyloxycarbonyl)urea hydrochloride (tautomer); N-Cbz-3-Aminomethylaniline HCl; Carbobenzyloxy-3-aminomethylaniline hydrochloride; Benzy (3-(aminomethyl)phenyl)carbamate hydrochloride; 3-(Cbz-amino)methylaniline HCl; (3-Aminobenzyl)carbamic acid benzyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our 3-n-Cbz-Aminomethylaniline Hcl is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are available upon request. We adhere to relevant cGMP guidelines for the manufacture of pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.