Description

4-(Piperidin-4-Yl)Aniline Hydrochloride is a versatile and high-value pharmaceutical intermediate and building block. This compound is crucial for the synthesis of complex molecules, particularly in medicinal chemistry and drug discovery programs. It is primarily sought after by research institutions and pharmaceutical companies for the development of new therapeutic agents, including kinase inhibitors and other small molecule drugs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for targeted cancer therapies.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop novel drug candidates.
• Kinase Inhibitor Synthesis: Serves as a core scaffold for the development of protein kinase inhibitors, a major class of oncology drugs.
• Chemical Biology Probes: Utilized in the creation of molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Employed in university and institutional labs for fundamental organic synthesis and pharmacological research.

Basic Information

Product Name	4-(Piperidin-4-Yl)Aniline Hydrochloride
CAS No.	1159824-20-0
Molecular Formula	C11H17ClN2
Molecular Weight	212.72 g/mol
Synonyms	4-(4-Aminophenyl)piperidine hydrochloride; 4-(Piperidin-4-yl)benzenamine hydrochloride; 4-Aminophenylpiperidine hydrochloride; 1-(4-Aminophenyl)-4-piperidinol hydrochloride (tautomer); 4-Piperidin-4-ylaniline HCl; Benzenamine, 4-(4-piperidinyl)-, hydrochloride; 4-(4-Piperidyl)aniline hydrochloride
EINECS	Contact for details

Quality Control

Our 4-(Piperidin-4-Yl)Aniline Hydrochloride is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP (current Good Manufacturing Practice) standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.