Description

1,4-Diaza-Spiro[5.5]Undecane Dihydrochloride is a high-purity, functionalized spirocyclic amine salt that serves as a critical building block in advanced organic synthesis. Its rigid, three-dimensional spirocyclic structure is highly valued for modulating the physicochemical properties and biological activity of target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and metabolic disease targets.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where its spirocyclic core can contribute to unique modes of action.
• Ligand and Catalyst Development: Serves as a sophisticated scaffold for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probe: Employed in the design of molecular probes for studying enzyme function and biological pathways.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific thermal or mechanical properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	1,4-Diaza-Spiro[5.5]Undecane Dihydrochloride
CAS No.	1159822-91-9
Molecular Formula	C9H18N2·2HCl
Molecular Weight	239.17 g/mol
Synonyms	1,4-Diazaspiro[5.5]undecane dihydrochloride; 1,4-Diaza-spiro[5.5]undecane hydrochloride; Spiro[5.5]undecane-1,4-diamine dihydrochloride; 1,4-Diazaspiro[5.5]undecane, hydrochloride (1:2); 1,4-Diazaspiro[5.5]undecane HCl salt
EINECS	Contact for details

Quality Control

Our 1,4-Diaza-Spiro[5.5]Undecane Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP guidelines for early-phase development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert conditions (e.g., nitrogen atmosphere) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.