Description

5-Benzyl-2,5-Diaza-Spiro[3.4]Octanedihydrochloride is a high-purity, advanced pharmaceutical intermediate belonging to the spirocyclic diaza compound class. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily sought by pharmaceutical R&D teams, contract research organizations (CROs), and fine chemical manufacturers engaged in innovative drug discovery and process development.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug candidates targeting neurological disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing spirocyclic libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• API Development: Serves as a key chiral building block for the development of new Active Pharmaceutical Ingredients (APIs) with potential therapeutic applications.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up synthesis under cGMP conditions.
• Biochemical Tool Compound: Utilized in academic and industrial research as a probe to study specific biological pathways and enzyme interactions.

Basic Information

Product Name	5-Benzyl-2,5-Diaza-Spiro[3.4]Octanedihydrochloride
CAS No.	1159822-76-0
Molecular Formula	C14H20N2·2HCl
Molecular Weight	297.24 g/mol (Free base: 224.33 g/mol)
Synonyms	5-Benzyl-2,5-diazaspiro[3.4]octane dihydrochloride; 2,5-Diaza-spiro[3.4]octane, 5-benzyl-, dihydrochloride; 5-Benzyl-2,5-diaza-spiro[3.4]octane hydrochloride; 5-Benzyl-2,5-diazaspiro[3.4]octane HCl; BDSO dihydrochloride; CAS 1159822-76-0; 5-Benzyl-2,5-diaza-spiro[3.4]octane, 2HCl
EINECS	Contact for details

Quality Control

Our 5-Benzyl-2,5-Diaza-Spiro[3.4]Octanedihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Assay (Titration)	97.0% - 103.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.