Description

Azepan-3-Ylamine Dihydrochloride is a high-purity, versatile organic building block and pharmaceutical intermediate. Its functionalized azepane (seven-membered nitrogen heterocycle) structure makes it a valuable scaffold for medicinal chemistry research and the synthesis of novel active pharmaceutical ingredients (APIs). This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries developing new therapeutic agents and specialty molecules.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of central nervous system (CNS) drugs, enzyme inhibitors, and receptor modulators.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies due to its constrained ring system and amine functionality.
• Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Employed in the creation of chiral ligands for asymmetric synthesis and organocatalysts.
• Chemical Biology Probes: Utilized for labeling, bioconjugation, and the development of molecular probes for biological target identification.
• Custom Synthesis and Contract Manufacturing: A starting material for the custom synthesis of complex organic molecules under cGMP or research-grade conditions.

Basic Information

Product Name	Azepan-3-Ylamine Dihydrochloride
CAS No.	1159822-22-6
Molecular Formula	C6H16Cl2N2
Molecular Weight	187.11 g/mol
Synonyms	3-Aminoazepane Dihydrochloride; Hexahydro-1H-azepin-3-amine Dihydrochloride; 3-Azepanamine Dihydrochloride; 1H-Azepin-3-amine, Hexahydro-, Dihydrochloride; Azepan-3-amine Dihydrochloride; 3-Aminohexamethyleneimine Dihydrochloride; 3-Amino-perhydroazepine Dihydrochloride
EINECS	Contact for details

Quality Control

Our Azepan-3-Ylamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR) to ensure it meets the stringent requirements for advanced research and development. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.