Description

1,8-Diaza-Spiro[4.5]Decane 2Hcl is a high-purity, spirocyclic diamine hydrochloride salt, a versatile and valuable building block in advanced organic synthesis. Its rigid, three-dimensional structure makes it a critical intermediate for developing novel pharmaceuticals and agrochemicals. This compound is essential for researchers and manufacturers in medicinal chemistry, particularly for creating complex molecules with specific biological activities.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug discovery.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its spirocyclic scaffold.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers, dendrimers, and other advanced materials requiring rigid, nitrogen-containing linkers.
• Chemical Biology Probes: Utilized to construct molecular probes and tools for studying biological pathways and protein interactions.

Basic Information

Product Name	1,8-Diaza-Spiro[4.5]Decane 2Hcl
CAS No.	1159822-20-4
Molecular Formula	C8H18N2·2HCl
Molecular Weight	223.16 g/mol
Synonyms	1,8-Diazaspiro[4.5]decane dihydrochloride; 1,8-Diaza-spiro[4.5]decane hydrochloride; Spiro[4.5]decane-1,8-diamine dihydrochloride; 1,8-Diazaspiro[4.5]decane, hydrochloride (1:2); 1,8-Diaza-Spiro[4.5]Decane 2HCl; 1,8-Diazaspiro[4.5]decane bis(hydrochloride); 1,8-Diazaspiro[4.5]decane HCl salt
EINECS	Contact for details

Quality Control

Our 1,8-Diaza-Spiro[4.5]Decane 2Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under dry, inert conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.