Description

1-(2-Aminoethyl)-n-Boc-Cyclohexylaminehydrochloride is a protected amine derivative used as a key building block in advanced organic synthesis. This compound is critical for the controlled introduction of a functionalized cyclohexylamine moiety into complex molecular architectures, ensuring high selectivity and yield. It is primarily needed by pharmaceutical R&D and fine chemical manufacturers for applications in peptide mimetics, linker chemistry, and the development of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and other therapeutic areas.
• Peptide Mimetics & Conjugates: Used to incorporate rigid, functionalized cyclohexyl structures into peptide backbones to enhance metabolic stability and binding affinity.
• Linker Chemistry: Serves as a versatile spacer or linker unit in the construction of PROTACs (Proteolysis Targeting Chimeras), antibody-drug conjugates (ADCs), and other bifunctional molecules.
• Chemical Biology Probes: Employed in the development of molecular probes and tools for studying biological pathways and protein function.
• Agrochemical Synthesis: Acts as an intermediate in the production of advanced crop protection agents requiring specific amine functionalities.
• Material Science Research: Utilized in the synthesis of specialty polymers and functional materials where precise amine group placement is required.

Basic Information

Product Name	1-(2-Aminoethyl)-n-Boc-Cyclohexylaminehydrochloride
CAS No.	1159822-19-1
Molecular Formula	C13H27ClN2O2
Molecular Weight	278.82 g/mol
Synonyms	1-(2-Aminoethyl)-N-Boc-cyclohexanamine hydrochloride; tert-Butyl N-[1-(2-aminoethyl)cyclohexyl]carbamate hydrochloride; N-Boc-1-(2-aminoethyl)cyclohexylamine HCl; 1-(2-Aminoethyl)cyclohexylamine, N-Boc, hydrochloride; Boc-1-(2-aminoethyl)cyclohexylamine HCl; Cyclohexanamine, 1-(2-aminoethyl)-, N-[(1,1-dimethylethoxy)carbonyl]-, hydrochloride; 1-(2-Aminoethyl)cyclohexanamine, N-Boc-protected, hydrochloride salt
EINECS	Contact for details

Quality Control

Our 1-(2-Aminoethyl)-n-Boc-Cyclohexylaminehydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.