Description

1-Pyridin-2-Ylcyclobutanecarboxylic Acid is a specialized heterocyclic carboxylic acid building block of significant interest in advanced organic synthesis. This compound matters for its unique structural motif, which combines a cyclobutane ring with a pyridine nitrogen, offering a constrained scaffold for medicinal chemistry and materials science research. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers developing novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Ligand Synthesis: Used to prepare complex chelating ligands for catalysis and metal-organic frameworks (MOFs).
• Agrochemical Research: Serves as a building block for creating new pesticides and herbicides with novel modes of action.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including ring-opening and cross-coupling reactions.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	1-Pyridin-2-Ylcyclobutanecarboxylic Acid
CAS No.	1159632-71-9
Molecular Formula	C10H11NO2
Molecular Weight	177.20 g/mol
Synonyms	2-(1-Carboxycyclobutyl)pyridine; 1-(Pyridin-2-yl)cyclobutanecarboxylic acid; Cyclobutanecarboxylic acid, 1-(2-pyridinyl)-; 1-(2-Pyridyl)cyclobutanecarboxylic acid; 1-Pyridin-2-yl-cyclobutanecarboxylic acid; 1-(Pyridin-2-yl)cyclobutan-1-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-Pyridin-2-Ylcyclobutanecarboxylic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and other relevant techniques. Our quality commitment supports applications requiring high-purity building blocks for research and cGMP-compliant development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The product is stable under these conditions but should be kept away from strong acids and oxidizing agents. For long-term storage, consider inert atmosphere packaging to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.