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2-Amino-6-Bromo-4-(Pentafluorosulphanyl)Phenol, 3-Bromo-2-Hydroxy-5-(Pentafluorosulphanyl)Aniline CAS NO 1159512-29-4
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CAS No.:1159512-29-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2-Amino-6-Bromo-4-(Pentafluorosulphanyl)Phenol, 3-Bromo-2-Hydroxy-5-(Pentafluorosulphanyl)Aniline is a high-value, multifunctional aromatic building block distinguished by its unique combination of bromine and pentafluorosulfanyl (SF5) substituents. This compound matters for its role in advanced material science and pharmaceutical research, where the SF5 group is prized for imparting exceptional lipophilicity, thermal stability, and metabolic resistance. It is primarily needed by R&D chemists and process development scientists in the agrochemical, pharmaceutical, and specialty polymer industries for creating novel active ingredients and high-performance materials.
Application
- Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the bioisosteric properties of the pentafluorosulfanyl group.
- Agrochemical Active Ingredient Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides where enhanced environmental stability and efficacy are required.
- Liquid Crystal & OLED Material Research: Functions as a key monomer for constructing advanced organic electronic materials, leveraging the SF5 group's influence on molecular polarity and charge transport properties.
- Polymer Modification: Employed to introduce bromine and fluorine functionalities into polymer backbones, improving flame retardancy, chemical resistance, and surface properties.
- Cross-Coupling Reactions: The bromine atom provides an excellent handle for palladium-catalyzed reactions (e.g., Suzuki, Sonogashira), enabling rapid diversification of the molecular scaffold.
- Fluorinated Dye & Pigment Development: Acts as a building block for creating dyes with superior lightfastness and unique color properties for niche industrial applications.
Basic Information
| Item | Details |
|---|---|
| Product Name | 2-Amino-6-Bromo-4-(Pentafluorosulphanyl)Phenol, 3-Bromo-2-Hydroxy-5-(Pentafluorosulphanyl)Aniline |
| CAS No. | 1159512-29-4 |
| Molecular Formula | C6H4BrF5NOS |
| Molecular Weight | 312.07 g/mol |
| Synonyms | 3-Bromo-2-hydroxy-5-(pentafluoro-λ6-sulfanyl)aniline; 2-Amino-6-bromo-4-(pentafluorosulfanyl)phenol; 6-Bromo-4-(pentafluorosulfanyl)benzene-1,3-diol; 2-Hydroxy-3-bromo-5-(pentafluorosulfanyl)aniline; 3-Bromo-5-(pentafluorosulfanyl)benzene-1,2-diamine (tautomer); SF5-Aniline derivative; Brominated SF5-phenol |
| EINECS | Contact for details |
Quality Control
Our 2-Amino-6-Bromo-4-(Pentafluorosulphanyl)Phenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency, meeting the stringent requirements of research and process chemistry. Standard quality verification includes HPLC for purity, NMR for structural confirmation, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening the primary container to prevent degradation. Keep away from strong oxidizing agents.
Specification
| Item | Specification |
|---|---|
| Appearance | Off-white to light yellow crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Melting Point | Contact for details |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals (as Pb) | ≤ 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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