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5-[[3,4,6-Tri-o-Acetyl-2-(Acetylamino)-2-Deoxy-β-D-Galactopyranosyl]Oxy]Pentanoic Acid Phenylmethyl Ester CAS NO 1159408-53-3


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CAS No.:1159408-53-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

5-[[3,4,6-Tri-o-Acetyl-2-(Acetylamino)-2-Deoxy-β-D-Galactopyranosyl]Oxy]Pentanoic Acid Phenylmethyl Ester is a sophisticated, protected glycosyl donor intermediate of significant value in synthetic carbohydrate chemistry. This compound matters because it provides a crucial, reactive building block for the controlled synthesis of complex oligosaccharides and glycoconjugates. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel glycotherapeutics, vaccines, and diagnostic tools.

Application

  • Glycoconjugate Synthesis: A key protected intermediate for the chemical synthesis of complex oligosaccharides and glycopeptides.
  • Pharmaceutical Research: Used in the development of carbohydrate-based drugs, including anticancer agents and anti-inflammatory therapeutics.
  • Vaccine Development: Serves as a building block for creating synthetic carbohydrate antigens for conjugate vaccines.
  • Biochemical Tool: Employed in enzymatic and chemoenzymatic studies to understand glycosylation pathways.
  • Glycochip Fabrication: Used to create functionalized surfaces for glycan array technology and biosensor development.
  • Standards and Reference Material: Acts as a high-purity analytical standard for quality control in glycobiology research.

Basic Information

Product Name 5-[[3,4,6-Tri-o-Acetyl-2-(Acetylamino)-2-Deoxy-β-D-Galactopyranosyl]Oxy]Pentanoic Acid Phenylmethyl Ester
CAS No. 1159408-53-3
Molecular Formula C28H37NO12
Molecular Weight 579.60 g/mol
Synonyms Benzyl 5-((3,4,6-tri-O-acetyl-2-acetamido-2-deoxy-β-D-galactopyranosyl)oxy)pentanoate; Benzyl 5-(((2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-galactopyranosyl)oxy))pentanoate; Phenylmethyl 5-[[3,4,6-Tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentanoate; N-Acetyl-3,4,6-tri-O-acetyl-β-D-galactosamine Benzyl Pentanoate Ester; Protected GalNAc Donor Ester; Glycosyl Donor Intermediate CAS 1159408-53-3
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Quality Control

Our 5-[[3,4,6-Tri-o-Acetyl-2-(Acetylamino)-2-Deoxy-β-D-Galactopyranosyl]Oxy]Pentanoic Acid Phenylmethyl Ester is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, typically exceeding 95% (HPLC). Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles via techniques such as NMR, HPLC, and MS. We adhere to cGMP principles where applicable to support its use in pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. This compound is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to ambient conditions or light may lead to decomposition. For long-term storage, consider storing under an inert atmosphere.

Specification

Item Specification
Appearance White to off-white solid
Identification (NMR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 1.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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