Description

1-(3-Nitrobenzyl)Piperidin-4-Amine Dihydrochloride is a high-purity, pharmaceutically relevant organic salt used as a critical building block in advanced chemical synthesis. This compound is valued for its role as a versatile intermediate in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily sought by research institutions, pharmaceutical development companies, and fine chemical manufacturers engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Chemical Synthesis Building Block: Serves as a versatile amine component for constructing complex molecular architectures in organic chemistry.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Biochemical Research: Utilized in the study of biological pathways and receptor interactions where its specific chemical structure is required.
• Process Development: Used in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.

Basic Information

Product Name	1-(3-Nitrobenzyl)Piperidin-4-Amine Dihydrochloride
CAS No.	1158785-53-5
Molecular Formula	C12H18N3O2 · 2HCl
Molecular Weight	324.22 g/mol (as dihydrochloride salt)
Synonyms	4-Amino-1-(3-nitrobenzyl)piperidine dihydrochloride; 1-[(3-Nitrophenyl)methyl]-4-piperidinamine dihydrochloride; 1-(3-Nitrobenzyl)-4-aminopiperidine dihydrochloride; 4-Piperidinamine, 1-[(3-nitrophenyl)methyl]-, dihydrochloride; 1-(3-Nitrobenzyl)piperidin-4-ylamine dihydrochloride; 3-Nitrobenzyl-4-aminopiperidine dihydrochloride
EINECS	Contact for details

Quality Control

Our 1-(3-Nitrobenzyl)Piperidin-4-Amine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the stringent requirements for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with the agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm
Assay (Titration)	97.0% - 103.0% (on anhydrous basis)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.