Description

5-(3-Fluorophenyl)Picolinic Acid is a high-purity fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which combines a picolinic acid scaffold with a fluorinated phenyl ring, enabling precise modulation of physicochemical properties in target molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and plant growth regulators, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Ligand Synthesis: Serves as a precursor for creating complex chelating ligands in coordination chemistry and catalysis.
• Material Science Precursor: Employed in the development of advanced organic electronic materials and metal-organic frameworks (MOFs).
• Chemical Biology Probe Development: Utilized to create fluorinated analogs of bioactive molecules for structure-activity relationship (SAR) studies.

Basic Information

Product Name	5-(3-Fluorophenyl)Picolinic Acid
CAS No.	1158763-55-3
Molecular Formula	C12H8FNO2
Molecular Weight	217.20 g/mol
Synonyms	5-(3-Fluorophenyl)pyridine-2-carboxylic acid; 2-Pyridinecarboxylic acid, 5-(3-fluorophenyl)-; 5-(3-Fluorophenyl)-2-pyridinecarboxylic acid; 5-(m-Fluorophenyl)picolinic acid; 3-Fluoro-5-(2-carboxypyridin-5-yl)benzene; 5-(3-Fluorophenyl)-2-carboxypyridine
EINECS	Contact for details

Quality Control

Every batch of 5-(3-Fluorophenyl)Picolinic Acid is manufactured under a strict quality management system and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our standard grade meets a typical purity specification of ≥97% (HPLC), with higher purity grades available. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.