Description

4-(Boc-Aminomethyl)-4-Methylpiperidine Hydrochloride is a protected amine derivative, specifically a tert-butyloxycarbonyl (Boc)-protected piperidine building block. This compound is a critical intermediate in the synthesis of complex molecules, offering a versatile handle for further functionalization while protecting the amine group from unwanted reactions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing active pharmaceutical ingredients (APIs) and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry for creating libraries of compounds.
• Peptide Mimetics & Modifications: Used to introduce constrained, substituted piperidine scaffolds into peptide chains to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a precursor in the development of new pesticides and herbicides that require specific amine functionalities.
• Ligand & Catalyst Development: Employed in the preparation of chiral ligands and organocatalysts for asymmetric synthesis.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules in research applications to study biological pathways.
• Custom Synthesis & Scale-Up: A starting material for contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects from milligram to kilogram scale.

Basic Information

Product Name	4-(Boc-Aminomethyl)-4-Methylpiperidine Hydrochloride
CAS No.	1158759-03-5
Molecular Formula	C12H24N2O2·HCl
Molecular Weight	264.79 g/mol
Synonyms	4-[(tert-Butoxycarbonylamino)methyl]-4-methylpiperidine hydrochloride; 4-Methyl-4-[(Boc-amino)methyl]piperidine HCl; 1-Boc-4-(aminomethyl)-4-methylpiperidine hydrochloride; 4-(Boc-aminomethyl)-4-methylpiperidine HCl; tert-Butyl [1-(4-methylpiperidin-4-yl)methyl]carbamate hydrochloride; N-Boc-4-(aminomethyl)-4-methylpiperidine hydrochloride; 4-(N-Boc-aminomethyl)-4-methylpiperidine hydrochloride
EINECS	Contact for details

Quality Control

Our 4-(Boc-Aminomethyl)-4-Methylpiperidine Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) with batch-specific data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.