Description

5-Fluoro-2-Piperidin-4-Yl-1H-Benzoimidazole Dihydrochloride is a high-purity, advanced pharmaceutical intermediate and research chemical. This compound is a critical building block in medicinal chemistry, valued for its role in the synthesis of novel bioactive molecules targeting various therapeutic areas. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for developing new chemical entities.
• Biochemical Tool Compound: Serves as a reference standard or probe in biochemical assays to study specific biological pathways and enzyme interactions.
• Active Pharmaceutical Ingredient (API) Development: Employed in the research and early-stage development of new APIs requiring the benzoimidazole-piperidine scaffold.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Academic Research: Used in university and institutional labs for fundamental research in organic synthesis and pharmacology.

Basic Information

Product Name	5-Fluoro-2-Piperidin-4-Yl-1H-Benzoimidazole Dihydrochloride
CAS No.	1158645-51-2
Molecular Formula	C₁₂H₁₅Cl₂FN₄
Molecular Weight	305.18 g/mol
Synonyms	5-Fluoro-2-(4-piperidinyl)-1H-benzimidazole dihydrochloride; 2-(Piperidin-4-yl)-5-fluoro-1H-benzoimidazole dihydrochloride; 5-Fluoro-2-(piperidin-4-yl)-1H-benzo[d]imidazole dihydrochloride; 1H-Benzimidazole, 5-fluoro-2-(4-piperidinyl)-, dihydrochloride; 1158645-51-2; 5-Fluoro-2-piperidin-4-yl-1H-benzoimidazole dihydrochloride
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-Piperidin-4-Yl-1H-Benzoimidazole Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.