Description

4-(Piperazinomethyl)Benzonitrile, Hydrochloride is a high-purity pharmaceutical intermediate and building block of significant importance in modern organic synthesis. Its core value lies in its versatile piperazine-linked benzonitrile structure, which is a key motif for constructing molecules with targeted biological activity. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its heterocyclic structure.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies.
• Ligand and Catalyst Preparation: Utilized in the preparation of specialized ligands for catalysis and metal complexation.
• Custom Synthesis Projects: A starting material for contract research organizations (CROs) and CDMOs working on proprietary compounds.

Basic Information

Product Name	4-(Piperazinomethyl)Benzonitrile, Hydrochloride
CAS No.	1158548-82-3
Molecular Formula	C12H16N4·HCl
Molecular Weight	252.74 g/mol
Synonyms	4-(Piperazin-1-ylmethyl)benzonitrile hydrochloride; 1-[(4-Cyanophenyl)methyl]piperazine hydrochloride; Benzonitrile, 4-(1-piperazinylmethyl)-, hydrochloride; Piperazine, 1-[(4-cyanophenyl)methyl]-, hydrochloride; 4-(Piperazin-1-ylmethyl)benzonitrile HCl; 4-Piperazin-1-ylmethyl-benzonitrile hydrochloride
EINECS	Contact for details

Quality Control

Our 4-(Piperazinomethyl)Benzonitrile, Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.