Description

5-Bromo-8-Methyl-1,2,3,4-Tetrahydroquinoline is a high-purity, advanced pharmaceutical intermediate and versatile heterocyclic building block. This compound is valued for its unique brominated and methylated tetrahydroquinoline scaffold, which is crucial for constructing complex molecules in medicinal chemistry. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive heterocyclic structure.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and other transformations to introduce functional complexity.
• Material Science: Investigated as a monomer or precursor for creating specialty polymers and organic electronic materials.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein interactions.

Basic Information

Product Name	5-Bromo-8-Methyl-1,2,3,4-Tetrahydroquinoline
CAS No.	1157721-71-5
Molecular Formula	C10H12BrN
Molecular Weight	226.11 g/mol
Synonyms	8-Methyl-5-bromo-1,2,3,4-tetrahydroquinoline; 5-Bromo-8-methyl-1,2,3,4-tetrahydroquinoline; 1,2,3,4-Tetrahydro-5-bromo-8-methylquinoline; 5-Bromo-8-methyl-1,2,3,4-tetrahydro-quinoline; 1157721-71-5
EINECS	Contact for details

Quality Control

Our 5-Bromo-8-Methyl-1,2,3,4-Tetrahydroquinoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing all specifications and test results. We adhere to cGMP principles for pharmaceutical-grade intermediates, ensuring traceability and reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (HPLC)	≥ 99.0% (High Purity Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.