Description

1-(5-Aminoquinolin-6-Yl)Piperidin-4-Ol is a high-purity, advanced pharmaceutical intermediate featuring a unique quinoline-piperidine hybrid structure. This compound is critical for the research and development of novel therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers seeking reliable, high-quality building blocks for complex synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting kinase inhibition.
• Oncology Research: Used in the development of novel small-molecule inhibitors for cancer therapy.
• CNS Drug Discovery: Serves as a core scaffold for compounds designed to cross the blood-brain barrier for treating neurological disorders.
• Chemical Biology Probes: Utilized in the creation of molecular probes to study specific biological pathways and protein functions.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale production of active pharmaceutical ingredients (APIs).
• Academic & Institutional Research: Provides a versatile starting material for synthetic chemistry and medicinal chemistry programs.

Basic Information

Product Name	1-(5-Aminoquinolin-6-Yl)Piperidin-4-Ol
CAS No.	1157642-42-6
Molecular Formula	C14H17N3O
Molecular Weight	243.31 g/mol
Synonyms	4-Piperidinol, 1-(5-amino-6-quinolinyl)-; 1-(5-Aminoquinolin-6-yl)piperidin-4-ol; 6-(4-Hydroxypiperidin-1-yl)quinolin-5-amine; 5-Amino-6-(4-hydroxypiperidin-1-yl)quinoline; 1-(5-Amino-6-quinolyl)piperidin-4-ol; 1157642-42-6; 5-Amino-6-(4-hydroxy-1-piperidinyl)quinoline
EINECS	Contact for details

Quality Control

Our 1-(5-Aminoquinolin-6-Yl)Piperidin-4-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.