Description

trans-2-([1,1'-Biphenyl]-4-Yl)Cyclopropane-1-Carboxylic Acid is a high-purity, synthetically derived carboxylic acid featuring a biphenyl-substituted cyclopropane core structure. This compound is valued as a versatile and critical pharmaceutical intermediate and research chemical for the development of novel active ingredients. It is primarily sought by R&D and manufacturing teams in the pharmaceutical, agrochemical, and advanced material science sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators due to its rigid, three-dimensional structure.
• Liquid Crystal & OLED Material Precursor: Serves as a core component for synthesizing advanced organic electronic materials requiring specific biphenyl-based motifs.
• Organic Synthesis Reagent: Employed in academic and industrial research for cyclopropanation studies and as a chiral synthon in asymmetric synthesis.
• Ligand & Catalyst Development: The carboxylic acid functionality allows for derivatization into chelating ligands for metal-catalyzed reactions.

Basic Information

Product Name	trans-2-([1,1'-Biphenyl]-4-Yl)Cyclopropane-1-Carboxylic Acid
CAS No.	1157562-54-3
Molecular Formula	C16H14O2
Molecular Weight	238.28 g/mol
Synonyms	trans-2-(4-Biphenylyl)cyclopropanecarboxylic Acid; 2-([1,1'-Biphenyl]-4-yl)cyclopropane-1-carboxylic Acid; 4-(trans-2-Carboxycyclopropyl)biphenyl; Biphenyl-4-cyclopropanecarboxylic Acid; (1R,2S)-rel-2-(4-Phenylphenyl)cyclopropanecarboxylic Acid; (1S,2R)-rel-2-(4-Phenylphenyl)cyclopropanecarboxylic Acid; Biphenyl Cyclopropane Carboxylic Acid Derivative
EINECS	Contact for details

Quality Control

Our trans-2-([1,1'-Biphenyl]-4-Yl)Cyclopropane-1-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.