Description

2-{[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]Amino}-2-Methyl-1-Propanol is a specialized pyridine derivative building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique trifluoromethyl and chloro-substituted pyridine core imparts desirable biological activity and metabolic stability. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors engaged in the synthesis of complex, high-value molecules.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-inflammatory agents, and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of next-generation pesticides, herbicides, and fungicides, leveraging the bioactivity of the trifluoromethylpyridine moiety.
• Chemical Research & Development: Serves as a versatile scaffold in academic and industrial R&D for exploring new chemical entities and reaction pathways.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-purity specialty chemicals for various technological applications.
• Ligand and Catalyst Development: Potential use in the creation of novel ligands for catalysis or metal-organic frameworks due to its nitrogen-containing heterocyclic structure.

Basic Information

Product Name	2-{[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]Amino}-2-Methyl-1-Propanol
CAS No.	1157109-01-7
Molecular Formula	C10H12ClF3N2O
Molecular Weight	268.66 g/mol
Synonyms	2-[(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino]-2-methylpropan-1-ol; 2-Methyl-1-propanol, 2-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]amino]-; 2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino)-2-methylpropan-1-ol; 2-[[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]amino]-2-methyl-1-propanol; 2-{[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]amino}-2-methylpropan-1-ol; 2-{[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2-methylpropan-1-ol
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material with a typical purity of ≥97% (by HPLC), tailored to meet specific project requirements. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request. Quality management adheres to cGMP principles for pharmaceutical-grade intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.