Description

1-(3-Bromophenyl)-1H-Pyrazole-4-Carboxylic Acid is a high-purity, functionalized pyrazole derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile scaffold for constructing complex molecules, particularly in pharmaceutical and agrochemical research and development. This compound is essential for medicinal chemists and process development scientists working on new active ingredients, where its bromophenyl and carboxylic acid moieties offer precise sites for further chemical modification.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the pyrazole core's bioactivity.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom synthesis projects and scale-up processes under cGMP conditions.
• Academic & Institutional Research: Used in universities and research institutes for exploratory chemistry and method development.

Basic Information

Product Name	1-(3-Bromophenyl)-1H-Pyrazole-4-Carboxylic Acid
CAS No.	1156994-32-9
Molecular Formula	C10H7BrN2O2
Molecular Weight	267.08 g/mol
Synonyms	3-Bromo-1H-pyrazole-4-carboxylic acid phenyl ester; 1-(3-Bromophenyl)-4-carboxypyrazole; 4-Carboxy-1-(3-bromophenyl)pyrazole; 1H-Pyrazole-4-carboxylic acid, 1-(3-bromophenyl)-; (3-Bromophenyl)pyrazole-4-carboxylic acid; 1156994-32-9; 1-(3-Bromophenyl)-1H-pyrazole-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-(3-Bromophenyl)-1H-Pyrazole-4-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our quality commitment supports applications requiring high-purity intermediates, from early-stage research to pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.