Description

8-Bromo-4-Chloro-6-Methylquinoline CAS NO 1156602-22-0 is a high-purity, multi-halogenated quinoline derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique reactivity profile, enabling the construction of complex molecular architectures essential for pharmaceutical and materials research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, antimicrobial agents, and other bioactive heterocycles.
• Agrochemical Research: Used in the creation of new active ingredients for crop protection products, leveraging its halogenated structure for enhanced biological activity.
• Material Science: Serves as a monomer or functional unit in the development of organic electronic materials, such as OLEDs and conductive polymers.
• Ligand Synthesis: Employed in the preparation of specialized nitrogen-containing ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology: Utilized as a molecular probe or a fluorescent tag precursor due to the quinoline core's photophysical properties.
• Academic & Contract Research: A versatile reagent for methodological development and exploratory synthesis in university and CRO laboratories.

Basic Information

Product Name	8-Bromo-4-Chloro-6-Methylquinoline
CAS No.	1156602-22-0
Molecular Formula	C₁₀H₇BrClN
Molecular Weight	256.53 g/mol
Synonyms	8-Bromo-4-chloro-6-methylquinoline; 4-Chloro-8-bromo-6-methylquinoline; 6-Methyl-8-bromo-4-chloroquinoline; Quinoline, 8-bromo-4-chloro-6-methyl-; 1156602-22-0; 8-Br-4-Cl-6-Me-Q
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch of 8-Bromo-4-Chloro-6-Methylquinoline is analyzed using advanced techniques including HPLC, GC, NMR, and mass spectrometry to confirm identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) with detailed chromatographic data are available upon request. We adhere to cGMP principles for manufacturing and quality management to ensure supply reliability and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.