Description

6-Bromo-7-Fluoro-3,4-Dihydroquinolin-2(1H)-One is a high-purity, advanced pharmaceutical intermediate characterized by its halogenated quinolinone core structure. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for synthesizing novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific bromo and fluoro substituents into complex molecular frameworks.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization due to its modifiable quinolinone scaffold.
• Agrochemical Development: Serves as a building block for creating novel herbicides and pesticides, leveraging the biological activity of halogenated heterocycles.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing specialized, high-value chemical entities.
• Academic & Institutional R&D: Utilized in university and research institute laboratories for exploring new chemical reactions and catalytic processes.

Basic Information

Product Name	6-Bromo-7-Fluoro-3,4-Dihydroquinolin-2(1H)-One
CAS No.	1156389-00-2
Molecular Formula	C9H7BrFNO
Molecular Weight	244.06 g/mol
Synonyms	6-Bromo-7-fluoro-1,2,3,4-tetrahydroquinolin-2-one; 6-Bromo-7-fluoro-3,4-dihydro-2(1H)-quinolinone; 2(1H)-Quinolinone, 6-bromo-7-fluoro-3,4-dihydro-; 6-Bromo-7-fluoro-1,2,3,4-tetrahydroquinolin-2-one; 6-Bromo-7-fluoro-3,4-dihydro-1H-quinolin-2-one
EINECS	Contact for details

Quality Control

Our 6-Bromo-7-Fluoro-3,4-Dihydroquinolin-2(1H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in its original packaging to minimize exposure to moisture and atmospheric contaminants. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.