Description

4-Chloro-5,7-Difluoro-2-Phenylquinoline is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique halogenated quinoline scaffold, which serves as a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in oncology and antimicrobial therapies.
• Agrochemical Synthesis: Used in the creation of advanced fungicides and herbicides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for OLEDs and other optoelectronic devices.
• Chemical Biology Probes: Utilized in the design of fluorescent probes and enzyme inhibitors for diagnostic and mechanistic studies.
• Academic & Contract Research: Essential for methodological development and exploratory synthesis in university and CRO laboratories.

Basic Information

Product Name	4-Chloro-5,7-Difluoro-2-Phenylquinoline
CAS No.	1155603-85-2
Molecular Formula	C15H8ClF2N
Molecular Weight	275.68 g/mol
Synonyms	2-Phenyl-4-chloro-5,7-difluoroquinoline; 4-Chloro-5,7-difluoro-2-phenyl-quinoline; 5,7-Difluoro-4-chloro-2-phenylquinoline; Quinoline, 4-chloro-5,7-difluoro-2-phenyl-; 1155603-85-2; 4-Chloro-5,7-difluoro-2-phenylquinoline
EINECS	Contact for details

Quality Control

Our 4-Chloro-5,7-Difluoro-2-Phenylquinoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.