Description

6,8-Difluoro-4-Hydroxy-2-Propylquinoline is a high-purity, fluorinated quinoline derivative serving as a critical advanced intermediate in modern organic synthesis. Its value lies in its unique molecular scaffold, which is essential for constructing complex pharmacophores and functional materials. This compound is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Research: Used in the development of next-generation herbicides and pesticides, leveraging the bioactivity of the quinoline core.
• Material Science Precursor: Serves as a monomer or precursor for creating specialty polymers, liquid crystals, or organic electronic materials.
• Chemical Synthesis Reagent: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis due to its modifiable functional groups.
• Fluorinated Compound Library: An important substrate for generating libraries of fluorinated compounds in drug discovery programs.
• Academic & Contract Research: Utilized in university and CRO laboratories for fundamental research in heterocyclic and fluorine chemistry.

Basic Information

Product Name	6,8-Difluoro-4-Hydroxy-2-Propylquinoline
CAS No.	1155600-14-8
Molecular Formula	C₁₂H₁₁F₂NO
Molecular Weight	223.22 g/mol
Synonyms	4-Hydroxy-6,8-difluoro-2-propylquinoline; 2-Propyl-6,8-difluoro-4-hydroxyquinoline; 6,8-Difluoro-4-hydroxy-2-propyl-1H-quinoline; 6,8-Difluoro-2-propyl-4-quinolinol; 4-Quinolinol, 6,8-difluoro-2-propyl-; 1155600-14-8 (CAS); DFHPQ
EINECS	Contact for details

Quality Control

Our 6,8-Difluoro-4-Hydroxy-2-Propylquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.