Description

1-(Pyridin-4-Yl)-1H-Pyrazole-4-Carboxylic Acid is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for lead optimization and scale-up activities.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Development: Used in the research and production of advanced crop protection agents and herbicides.
• Ligand Synthesis: Serves as a precursor for creating complex chelating ligands used in catalysis and material science.
• Material Science Research: Employed in the development of organic electronic materials and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized as a building block for creating tool compounds and probes to study biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and contract research organizations (CROs/CMOs).

Basic Information

Product Name	1-(Pyridin-4-Yl)-1H-Pyrazole-4-Carboxylic Acid
CAS No.	1155066-46-8
Molecular Formula	C9H7N3O2
Molecular Weight	189.17 g/mol
Synonyms	4-(1H-Pyrazol-4-yl)pyridine-1-carboxylic acid; 1-(4-Pyridinyl)-1H-pyrazole-4-carboxylic acid; 1H-Pyrazole-4-carboxylic acid, 1-(4-pyridinyl)-; 1155066-46-8; 4-Pyrazolecarboxylic acid, 1-(4-pyridinyl)-; 1-(Pyridin-4-yl)-1H-pyrazole-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-(Pyridin-4-Yl)-1H-Pyrazole-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specification results. Our quality commitment supports applications requiring high standards, including cGMP development and research under ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.