Description

6-Amino-7-Fluoro-1,2,3,4-Tetrahydroquinolin-2-One is a high-purity, advanced pharmaceutical intermediate featuring a fused quinolinone scaffold with strategic amino and fluoro substituents. This compound is of significant commercial importance as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular interactions. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing next-generation drugs and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Research: Serves as a core structure for developing new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Organic Synthesis Building Block: Used in academic and industrial R&D for constructing complex heterocyclic compounds and exploring novel chemical spaces.
• Fluorinated Compound Library: Essential for creating focused libraries of fluorinated molecules in medicinal chemistry for structure-activity relationship (SAR) studies.
• Material Science Precursor: Potential use in the development of specialty polymers, dyes, and advanced organic electronic materials.

Basic Information

Product Name	6-Amino-7-Fluoro-1,2,3,4-Tetrahydroquinolin-2-One
CAS No.	1155000-06-8
Molecular Formula	C9H9FN2O
Molecular Weight	180.18 g/mol
Synonyms	7-Fluoro-6-amino-3,4-dihydro-2(1H)-quinolinone; 6-Amino-7-fluoro-3,4-dihydro-2(1H)-quinolinone; 6-Amino-7-fluoro-1,2,3,4-tetrahydroquinolin-2-one; 2(1H)-Quinolinone, 6-amino-7-fluoro-3,4-dihydro-; 1155000-06-8; 6-Amino-7-fluoro-1,2,3,4-tetrahydroquinolin-2-one; 7-Fluoro-6-amino-1,2,3,4-tetrahydroquinolin-2-one
EINECS	Contact for details

Quality Control

Our 6-Amino-7-Fluoro-1,2,3,4-Tetrahydroquinolin-2-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.