Description

2-(Trifluoromethyl)-5,6,7,8-Tetrahydroquinoline-6-Carboxylicacid CAS NO 1154743-13-1 is a high-value, fluorinated heterocyclic building block characterized by its tetrahydroquinoline core and carboxylic acid functionality. This compound is essential for advanced research and development, particularly in the synthesis of complex molecules where the introduction of a trifluoromethyl group can dramatically alter physicochemical properties. It is primarily sought after by pharmaceutical and agrochemical research organizations for creating novel active ingredients and fine chemical intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the CF3 group enhances bioavailability and metabolic stability.
• Material Science Research: Serves as a precursor for specialty ligands, catalysts, and functionalized polymers with unique electronic properties.
• Fluorine Chemistry Studies: An important compound for investigating structure-activity relationships (SAR) and the effects of fluorination in heterocyclic systems.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for high-purity, complex organic molecules.

Basic Information

Product Name	2-(Trifluoromethyl)-5,6,7,8-Tetrahydroquinoline-6-Carboxylicacid
CAS No.	1154743-13-1
Molecular Formula	C11H10F3NO2
Molecular Weight	245.20 g/mol
Synonyms	6-Carboxy-2-(trifluoromethyl)-5,6,7,8-tetrahydroquinoline; 2-(Trifluoromethyl)-5,6,7,8-tetrahydroquinoline-6-carboxylic acid; 5,6,7,8-Tetrahydro-2-(trifluoromethyl)quinoline-6-carboxylic acid; 1154743-13-1; 6-Quinolinecarboxylic acid, 5,6,7,8-tetrahydro-2-(trifluoromethyl)-; Tetrahydro-2-(trifluoromethyl)quinoline-6-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 2-(Trifluoromethyl)-5,6,7,8-Tetrahydroquinoline-6-Carboxylicacid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support development and commercial projects requiring compliance with cGMP and ISO standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.