Description

Methyl 2-(Trifluoromethyl)Quinoline-6-Carboxylate is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in the strategic combination of a quinoline scaffold with a trifluoromethyl group and a methyl ester, offering versatile reactivity for constructing complex molecular architectures. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in therapeutic areas targeting CNS disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Serves as a crucial precursor in the manufacture of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Used in the synthesis of organic semiconductors, light-emitting materials, and specialty polymers due to the electron-deficient quinoline core.
• Ligand and Catalyst Development: Employed as a starting material for creating novel nitrogen-containing ligands used in catalytic processes.
• Fluorescent Probe Synthesis: The quinoline structure makes it suitable for developing fluorescent dyes and molecular probes for biochemical sensing and imaging.

Basic Information

Product Name	Methyl 2-(Trifluoromethyl)Quinoline-6-Carboxylate
CAS No.	1154743-11-9
Molecular Formula	C12H8F3NO2
Molecular Weight	255.19 g/mol
Synonyms	6-Quinolinecarboxylic acid, 2-(trifluoromethyl)-, methyl ester; Methyl 2-(trifluoromethyl)-6-quinolinecarboxylate; 2-Trifluoromethylquinoline-6-carboxylic acid methyl ester; Methyl 2-trifluoromethylquinoline-6-carboxylate; Quinoline-6-carboxylic acid, 2-(trifluoromethyl)-, methyl ester; CAS 1154743-11-9
EINECS	Contact for details

Quality Control

Our Methyl 2-(Trifluoromethyl)Quinoline-6-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.