Description

8-Bromo-5-Chloroquinoline is a high-purity halogenated quinoline derivative serving as a critical building block in advanced organic synthesis. Its value lies in its dual functionalization, providing distinct reactive sites for constructing complex heterocyclic scaffolds essential for pharmaceutical and agrochemical research. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinoline-based drug candidates, including potential antimicrobials, anticancer agents, and kinase inhibitors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging the bioactivity of the quinoline core.
• Material Science: Serves as a monomer or functionalizing agent in the creation of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Synthesis: Acts as a versatile reagent for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions to introduce complex functionalities.
• Ligand Synthesis: Utilized for preparing specialized nitrogen-containing ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	8-Bromo-5-Chloroquinoline
CAS No.	1154741-20-4
Molecular Formula	C9H5BrClN
Molecular Weight	242.50 g/mol
Synonyms	5-Chloro-8-bromoquinoline; 8-Bromo-5-chloroquinoline; Quinoline, 8-bromo-5-chloro-; 1154741-20-4
EINECS	Contact for details

Quality Control

Our 8-Bromo-5-Chloroquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.