Description

1-(2-Cyano-Benzyl)-Piperidine-4-Carboxylic Acid is a high-purity, synthetically versatile piperidine derivative and a key building block in advanced organic synthesis. Its molecular structure, featuring both a cyano-benzyl group and a carboxylic acid functionality, makes it a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Agrochemical Synthesis: Used as a building block for developing advanced pesticides and herbicides with specific biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating complex ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, dyes, and performance materials.
• Academic and R&D: Utilized in university and corporate research laboratories for methodological studies and exploring new chemical reactions.
• Peptidomimetic Chemistry: The piperidine-carboxylic acid core is valuable for designing and synthesizing peptide analogs and enzyme inhibitors.

Basic Information

Product Name	1-(2-Cyano-Benzyl)-Piperidine-4-Carboxylic Acid
CAS No.	1153070-82-6
Molecular Formula	C15H16N2O2
Molecular Weight	256.30 g/mol
Synonyms	1-[(2-Cyanophenyl)methyl]piperidine-4-carboxylic acid; 4-Piperidinecarboxylic acid, 1-[(2-cyanophenyl)methyl]-; 1-(2-Cyanobenzyl)isonipecotic acid; 1-(2-Cyanobenzyl)-4-piperidinecarboxylic acid; 1-(2-Cyanobenzyl)piperidine-4-carboxylic acid; Isonipecotic acid, 1-(2-cyanobenzyl)-; Piperidine-4-carboxylic acid, 1-(2-cyanobenzyl)-; 1153070-82-6
EINECS	Contact for details

Quality Control

Our 1-(2-Cyano-Benzyl)-Piperidine-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with key parameters including assay (HPLC), related substances, and residual solvents, supporting its use in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly closed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.