Description

6-Bromo-4-Chloro-2,8-Dimethylquinoline is a high-purity, multi-substituted quinoline derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique halogenated and alkylated structure makes it a valuable building block for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, antimicrobial agents, and other biologically active heterocycles.
• Agrochemical Research: Used to develop novel fungicides, herbicides, and insecticides, leveraging the quinoline scaffold's bioactivity.
• Material Science: Serves as a building block for organic light-emitting diodes (OLEDs), liquid crystals, and other advanced functional materials due to its electron-deficient aromatic system.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions to introduce complex quinoline motifs.
• Academic & Industrial R&D: A versatile reagent for method development and exploring new chemical space in heterocyclic and organometallic chemistry.

Basic Information

Product Name	6-Bromo-4-Chloro-2,8-Dimethylquinoline
CAS No.	1153002-90-4
Molecular Formula	C11H9BrClN
Molecular Weight	270.55 g/mol
Synonyms	4-Chloro-6-bromo-2,8-dimethylquinoline; 2,8-Dimethyl-6-bromo-4-chloroquinoline; Quinoline, 6-bromo-4-chloro-2,8-dimethyl-; 6-Bromo-4-chloro-2,8-dimethyl-quinoline
EINECS	Contact for details

Quality Control

Our 6-Bromo-4-Chloro-2,8-Dimethylquinoline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.