Description

8-Bromo-2-Chloro-7-Fluoroquinoline is a high-purity, multi-halogenated quinoline derivative serving as a critical building block in advanced organic synthesis. Its unique halogen substitution pattern makes it an indispensable intermediate for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs). This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel fluoroquinolone antibiotics and other therapeutic agents targeting bacterial infections.
• Agrochemical Research: Used in developing new generation pesticides and herbicides, leveraging its halogenated structure for enhanced bioactivity.
• Material Science: Serves as a monomer or functionalizing agent in the creation of organic electronic materials and fluorescent dyes.
• Chemical Biology: Employed as a molecular probe or tag due to its distinct spectroscopic properties for studying biological systems.
• Academic & Contract Research: Essential for methodological development and discovery chemistry in university and CRO laboratories worldwide.

Basic Information

Product Name	8-Bromo-2-Chloro-7-Fluoroquinoline
CAS No.	1152781-66-2
Molecular Formula	C9H4BrClFN
Molecular Weight	260.49 g/mol
Synonyms	8-Bromo-2-chloro-7-fluoroquinoline; 2-Chloro-8-bromo-7-fluoroquinoline; 7-Fluoro-8-bromo-2-chloroquinoline; Quinoline, 8-bromo-2-chloro-7-fluoro-; 1152781-66-2; 8-Br-2-Cl-7-F-quinoline
EINECS	Contact for details

Quality Control

Every batch of 8-Bromo-2-Chloro-7-Fluoroquinoline is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high standards required for research and development. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.