Description

[4-(4-Bromophenyl)Oxan-4-Yl]Methanamine is a high-purity, synthetically versatile organic building block featuring a brominated phenyl group tethered to an amine-functionalized tetrahydropyran (oxane) ring. This compound matters as a critical intermediate for medicinal chemistry and advanced materials research, enabling the construction of complex molecular architectures. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers developing novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty polymers.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of potential drug candidates, particularly in constructing central scaffolds for kinase inhibitors or CNS-active molecules.
• Agrochemical Research: Used in developing novel herbicides or fungicides, where the bromophenyl moiety can be further functionalized.
• Ligand & Catalyst Development: The amine group allows for chelation to metal centers, making it useful for creating novel ligands in catalytic systems.
• Material Science: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers with specific thermal or optical properties.
• Chemical Biology: Employed as a probe or linker in bioconjugation chemistry due to its reactive amine handle.
• Academic & Contract Research: Utilized in university and CRO laboratories for method development and exploring new synthetic pathways.

Basic Information

Product Name	[4-(4-Bromophenyl)Oxan-4-Yl]Methanamine
CAS No.	1152568-20-1
Molecular Formula	C12H16BrNO
Molecular Weight	270.17 g/mol
Synonyms	4-(4-Bromophenyl)tetrahydro-2H-pyran-4-ylmethanamine; 1-[4-(4-Bromophenyl)tetrahydropyran-4-yl]methanamine; (4-(4-Bromophenyl)tetrahydro-2H-pyran-4-yl)methanamine; 4-(Aminomethyl)-4-(4-bromophenyl)tetrahydro-2H-pyran; 4-(4-Bromophenyl)-4-(aminomethyl)tetrahydro-2H-pyran; 4-(4-Bromophenyl)-4-(aminomethyl)oxane
EINECS	Contact for details

Quality Control

Our [4-(4-Bromophenyl)Oxan-4-Yl]Methanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting customer specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.