Description

8-Bromo-2,3-Dihydro-1,4-Benzodioxine-6-Carboxylic Acid is a high-purity, functionalized benzodioxine derivative that serves as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of novel pharmaceuticals and agrochemicals, enabling the introduction of both bromine and carboxylic acid functionalities for further derivatization. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated benzodioxine core.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chelating ligands and organocatalysts in asymmetric synthesis.
• Material Science Monomer: Potential monomer for the synthesis of specialized polymers with unique electronic or optical properties.
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a molecular probe.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	8-Bromo-2,3-Dihydro-1,4-Benzodioxine-6-Carboxylic Acid
CAS No.	1152567-51-5
Molecular Formula	C9H7BrO4
Molecular Weight	259.06 g/mol
Synonyms	6-Carboxy-8-bromo-2,3-dihydro-1,4-benzodioxine; 8-Bromo-2,3-dihydro-1,4-benzodioxin-6-carboxylic acid; 8-Bromo-6-carboxy-2,3-dihydro-1,4-benzodioxine; 1,4-Benzodioxine-6-carboxylic acid, 8-bromo-2,3-dihydro-; 1152567-51-5; 8-Br-DHBD-6-COOH
EINECS	Contact for details

Quality Control

Our 8-Bromo-2,3-Dihydro-1,4-Benzodioxine-6-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent batch-to-batch quality suitable for research and scale-up. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.