Description

1-(3-Methyl-3-Azetidinyl)-Pyrrolidine 2Hcl is a high-purity, nitrogen-containing heterocyclic building block supplied as a dihydrochloride salt. This compound is valued for its role as a key intermediate in the synthesis of complex pharmaceutical molecules, particularly in medicinal chemistry research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for constructing novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization stages for constructing and diversifying molecular scaffolds.
• Process Chemistry Development: Serves as a starting material or intermediate in scaling up synthetic routes for Active Pharmaceutical Ingredients (APIs).
• Ligand Synthesis: Potential precursor for creating specialized ligands in catalysis or biochemical assays.
• Academic Research: Utilized in universities and research institutes for studying heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Product Name	1-(3-Methyl-3-Azetidinyl)-Pyrrolidine 2Hcl
CAS No.	1152111-80-2
Molecular Formula	C8H18Cl2N2
Molecular Weight	213.15 g/mol
Synonyms	1-(3-Methylazetidin-3-yl)pyrrolidine dihydrochloride; 3-(Pyrrolidin-1-yl)-3-methylazetidine dihydrochloride; 3-Methyl-3-(pyrrolidin-1-yl)azetidine hydrochloride (1:2); 1-(3-Methyl-3-azetidinyl)pyrrolidine hydrochloride; 3-Methyl-3-(pyrrolidin-1-yl)azetidine dihydrochloride
EINECS	Contact for details

Quality Control

Our 1-(3-Methyl-3-Azetidinyl)-Pyrrolidine 2Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.