Description

7-Bromo-1,5-Naphthyridin-4(1H)-One is a high-purity brominated naphthyridinone derivative, serving as a critical pharmaceutical intermediate and organic building block for advanced synthesis. Its value lies in enabling the construction of complex nitrogen-containing heterocycles, which are core scaffolds in modern drug discovery and materials science. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of kinase inhibitors, antiviral agents, and other bioactive molecules targeting naphthyridine-based pharmacophores.
• Agrochemical Research: Building block for developing novel herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Material Science: Used in the creation of organic semiconductors, ligands for metal-organic frameworks (MOFs), and advanced polymers.
• Chemical Biology: Serves as a probe or tag in biochemical assays and the development of molecular tools.
• Academic & Contract Research: Essential for methodological studies in organic synthesis and heterocyclic chemistry at universities and CROs.
• Custom Synthesis: Starting material for the contract manufacturing of proprietary compounds and fine chemicals.

Basic Information

Product Name	7-Bromo-1,5-Naphthyridin-4(1H)-One
CAS No.	1151802-14-0
Molecular Formula	C8H5BrN2O
Molecular Weight	225.04 g/mol
Synonyms	7-Bromo-1,5-naphthyridin-4(1H)-one; 4(1H)-7-Bromo-1,5-naphthyridinone; 7-Bromo-4-hydroxy-1,5-naphthyridine; 1,5-Naphthyridin-4(1H)-one, 7-bromo-; 7-Bromo-1H-1,5-naphthyridin-4-one; 7-Bromo-4(1H)-1,5-naphthyridinone; 7-Bromo-1,5-naphthyridin-4-ol
EINECS	Contact for details

Quality Control

Our 7-Bromo-1,5-Naphthyridin-4(1H)-One is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with detailed specifications upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.