Description

5,7-Difluoro-3-Hydroxyquinolin-2(1H)-One is a high-purity fluorinated quinolinone derivative, serving as a critical advanced pharmaceutical intermediate. Its value lies in its unique molecular scaffold, which is essential for synthesizing novel active pharmaceutical ingredients (APIs) with targeted biological activity. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in therapeutic areas requiring fluorinated heterocycles.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the difluoro-hydroxyquinolinone structure can contribute to bioactivity and stability.
• Organic Synthesis & Material Science: Acts as a versatile precursor for creating complex organic molecules and functional materials, including ligands for catalysis.
• Fluorescent Probe Development: The quinolinone core can be utilized in the design of fluorophores and sensors for biochemical and diagnostic applications.
• Academic & Contract Research: Serves as a valuable reagent for university laboratories and CROs (Contract Research Organizations) conducting fundamental chemical research.

Basic Information

Item	Details
Product Name	5,7-Difluoro-3-Hydroxyquinolin-2(1H)-One
CAS No.	1150618-29-3
Molecular Formula	C9H5F2NO2
Molecular Weight	197.14 g/mol
Synonyms	5,7-Difluoro-3-hydroxy-1H-quinolin-2-one; 5,7-Difluoro-3-hydroxy-2(1H)-quinolinone; 2(1H)-Quinolinone, 5,7-difluoro-3-hydroxy-; 3-Hydroxy-5,7-difluoroquinolin-2(1H)-one
EINECS	Contact for details

Quality Control

Our 5,7-Difluoro-3-Hydroxyquinolin-2(1H)-One is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.