Description

Methyl 7-Chloro-8-Fluoro-4-Hydroxyquinoline-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a defined molecular structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of next-generation antibacterial and antiviral agents. It is primarily required by research institutions, custom synthesis houses, and pharmaceutical manufacturers engaged in the development of complex heterocyclic compounds.

Application

• Key Intermediate in API Synthesis: Serves as a crucial building block for the production of complex fluoroquinolone and related antibacterial compounds.
• Pharmaceutical Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new therapeutic candidates.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.
• Chemical Reference Standard: Utilized as a high-purity standard for analytical method development and quality control in pharmaceutical labs.

Basic Information

Product Name	Methyl 7-Chloro-8-Fluoro-4-Hydroxyquinoline-2-Carboxylate
CAS No.	1150164-88-7
Molecular Formula	C12H7ClFNO3
Molecular Weight	267.64 g/mol
Synonyms	7-Chloro-8-fluoro-4-hydroxyquinoline-2-carboxylic acid methyl ester; Methyl 7-chloro-8-fluoro-4-hydroxy-2-quinolinecarboxylate; 2-Quinolinecarboxylic acid, 7-chloro-8-fluoro-4-hydroxy-, methyl ester; 1150164-88-7; 7-Chloro-8-fluoro-4-hydroxy-2-quinolinecarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 7-Chloro-8-Fluoro-4-Hydroxyquinoline-2-Carboxylate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the exacting standards required for pharmaceutical intermediate applications. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.