Description

4,7-Dichloro-8-Fluoro-2-(Trifluoromethyl)Quinoline is a high-value, multi-halogenated quinoline derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring chlorine, fluorine, and trifluoromethyl substituents, makes it an essential intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating compounds with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: Key synthon for the development of new drug candidates, particularly in antiviral, anticancer, and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides with improved efficacy.
• Material Science Research: Serves as a precursor for creating specialty chemicals and functional materials, such as organic semiconductors or ligands for catalysis.
• Fluorochemical Building Block: The trifluoromethyl and fluorine groups make it valuable for introducing fluorine into target molecules to alter their physical and chemical properties.
• Chemical Research & Development: A versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for proprietary synthesis projects.

Basic Information

Product Name	4,7-Dichloro-8-Fluoro-2-(Trifluoromethyl)Quinoline
CAS No.	1150164-86-5
Molecular Formula	C10H3Cl2F4N
Molecular Weight	284.04 g/mol
Synonyms	8-Fluoro-4,7-dichloro-2-(trifluoromethyl)quinoline; 2-(Trifluoromethyl)-4,7-dichloro-8-fluoroquinoline; Quinoline, 4,7-dichloro-8-fluoro-2-(trifluoromethyl)-; 4,7-Dichloro-8-fluoro-2-trifluoromethylquinoline; 1150164-86-5
EINECS	Contact for details

Quality Control

Our 4,7-Dichloro-8-Fluoro-2-(Trifluoromethyl)Quinoline is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and scale-up. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) are available for every batch, detailing all specified parameters to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.