Description

7-Chloro-8-Fluoro-2-(Trifluoromethyl)Quinolin-4-Ol is a high-value, multi-functionalized quinoline derivative that serves as a critical advanced intermediate in modern synthetic chemistry. Its unique halogenated and trifluoromethylated structure makes it indispensable for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, where the fluorine and chlorine substituents can enhance biological activity and environmental stability.
• Material Science: Serves as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Synthesis: Acts as a versatile scaffold for further functionalization in organic synthesis, enabling the creation of diverse compound libraries for screening.
• Academic & Industrial R&D: Employed in research laboratories for method development and studying structure-activity relationships (SAR) in various chemical fields.

Basic Information

Product Name	7-Chloro-8-Fluoro-2-(Trifluoromethyl)Quinolin-4-Ol
CAS No.	1150164-84-3
Molecular Formula	C₁₁H₄ClF₄NO
Molecular Weight	277.60 g/mol
Synonyms	4-Hydroxy-7-chloro-8-fluoro-2-(trifluoromethyl)quinoline; 7-Chloro-8-fluoro-2-(trifluoromethyl)-4-quinolinol; 7-Chloro-8-fluoro-2-trifluoromethylquinolin-4-ol; 4-Quinolinol, 7-chloro-8-fluoro-2-(trifluoromethyl)-; 1150164-84-3; CAS 1150164-84-3
EINECS	Contact for details

Quality Control

Our 7-Chloro-8-Fluoro-2-(Trifluoromethyl)Quinolin-4-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our commitment to quality ensures reliable performance in your most demanding synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.