Description

Methyl4,7-Dichloro-8-Fluoroquinoline-2-Carboxylate is a high-purity fluorinated quinoline derivative, a crucial advanced pharmaceutical intermediate. This compound is valued for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of antibacterial and antiviral agents. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers serving the global life sciences sector.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of next-generation fluoroquinolone antibiotics and other therapeutic agents.
• Antibacterial Drug Development: Used in research and production of compounds targeting DNA gyrase and topoisomerase IV enzymes.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization and the creation of complex heterocyclic libraries.
• Agrochemical Research: Potential intermediate in the development of novel crop protection agents with specific biological activity.
• Material Science: Investigated for use in the synthesis of organic electronic materials and fluorescent markers.

Basic Information

Product Name	Methyl4,7-Dichloro-8-Fluoroquinoline-2-Carboxylate
CAS No.	1150164-82-1
Molecular Formula	C12H6Cl2FNO2
Molecular Weight	286.09 g/mol
Synonyms	Methyl 4,7-Dichloro-8-fluoro-2-quinolinecarboxylate; 4,7-Dichloro-8-fluoroquinoline-2-carboxylic acid methyl ester; 8-Fluoro-4,7-dichloroquinoline-2-carboxylic acid methyl ester; Methyl 8-fluoro-4,7-dichloroquinoline-2-carboxylate; 2-Quinolinecarboxylic acid, 4,7-dichloro-8-fluoro-, methyl ester; CAS 1150164-82-1
EINECS	Contact for details

Quality Control

Our Methyl4,7-Dichloro-8-Fluoroquinoline-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.