Description

Methyl8-Bromo-4,6-Dichloroquinoline-2-Carboxylate is a high-purity, multi-halogenated quinoline derivative serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in providing a versatile, functionalized scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process R&D teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, antimicrobials, and other biologically active quinoline-based compounds.
• Agrochemical Research: Used in the discovery and synthesis of new pesticides and herbicides, leveraging the quinoline core's bioactivity.
• Material Science Precursor: Serves as a starting material for creating functionalized organic ligands used in catalysis or advanced organic electronic materials.
• Chemical Biology Probe Development: Utilized to create tagged or modified molecules for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules on a commercial scale.
• Academic & Institutional Research: Provides a standardized, high-quality reagent for methodology development and exploratory chemistry in university and government laboratories.

Basic Information

Product Name	Methyl8-Bromo-4,6-Dichloroquinoline-2-Carboxylate
CAS No.	1150164-76-3
Molecular Formula	C11H6BrCl2NO2
Molecular Weight	335.98 g/mol
Synonyms	Methyl 8-bromo-4,6-dichloroquinoline-2-carboxylate; 8-Bromo-4,6-dichloroquinoline-2-carboxylic acid methyl ester; 2-Quinolinecarboxylic acid, 8-bromo-4,6-dichloro-, methyl ester; Methyl 8-bromo-4,6-dichloro-2-quinolinecarboxylate
EINECS	Contact for details

Quality Control

Our Methyl8-Bromo-4,6-Dichloroquinoline-2-Carboxylate is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert atmosphere conditions to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.