Description

{1-[1-(5-Nitro-Pyridin-2-Yl)-1H-Benzoimidazol-2-Yl]-Piperidin-4-Yl}-Carbamic Acid tert-Butyl Ester, 98+% is a high-purity, advanced pharmaceutical intermediate with the molecular formula C22H26N6O4 and a molecular weight of 438.49. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel drug candidates targeting complex biological pathways. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug discovery programs.
• Process Chemistry Development: Serves as a critical intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Biochemical Probe Synthesis: Utilized to create labeled or modified compounds for biological mechanism of action studies.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and development services.
• Academic Research: Employed in university and institutional labs for cutting-edge chemical biology and drug discovery projects.

Basic Information

Product Name	{1-[1-(5-Nitro-Pyridin-2-Yl)-1H-Benzoimidazol-2-Yl]-Piperidin-4-Yl}-Carbamic Acid tert-Butyl Ester
CAS No.	1146080-64-9
Molecular Formula	C22H26N6O4
Molecular Weight	438.49 g/mol
Synonyms	tert-Butyl N-[1-[1-(5-nitropyridin-2-yl)benzimidazol-2-yl]piperidin-4-yl]carbamate; 1-[1-(5-Nitropyridin-2-yl)-1H-benzimidazol-2-yl]piperidine-4-carboxylic acid tert-butylamide (related form); BOC-protected nitro-pyridinyl-benzimidazolyl-piperidine carbamate; CAS 1146080-64-9; 4-[[(1,1-Dimethylethoxy)carbonyl]amino]-1-[1-(5-nitro-2-pyridinyl)-1H-benzimidazol-2-yl]piperidine; (1-[1-(5-Nitro-Pyridin-2-Yl)-1H-Benzoimidazol-2-Yl]-Piperidin-4-Yl)-Carbamic Acid tert-Butyl Ester
EINECS	Contact for details

Quality Control

Our 98+% purity grade of this advanced intermediate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and consistency for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. This compound is hygroscopic (moisture-sensitive) and should be stored in a cool, dry place, ideally at controlled room temperature (15-25°C). For long-term storage, consider desiccated conditions to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.