Description

3-(4-Chloro-Pyrimidin-2-Yl)-1H-Indole is a high-purity (98+%) heterocyclic organic compound with the molecular formula C12H8ClN3 and a molecular weight of 229.67. This specialized chemical building block is critical for research and development in medicinal chemistry, offering a versatile scaffold for creating novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of targeted small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in oncology and antiviral research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Kinase Inhibitor Development: The chloro-pyrimidine moiety makes it a valuable intermediate for developing protein kinase inhibitors.
• Agrochemical Synthesis: Potential use as a building block for creating new herbicides or fungicides with specific modes of action.
• Material Science Research: Can be investigated as a monomer or functional component in the development of advanced organic electronic materials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical and agrochemical development pipelines.

Basic Information

Product Name	3-(4-Chloro-Pyrimidin-2-Yl)-1H-Indole
CAS No.	1146080-35-4
Molecular Formula	C12H8ClN3
Molecular Weight	229.67 g/mol
Synonyms	1H-Indole, 3-(4-chloro-2-pyrimidinyl)-; 3-(4-Chloropyrimidin-2-yl)-1H-indole; 2-(1H-Indol-3-yl)-4-chloropyrimidine; 4-Chloro-2-(1H-indol-3-yl)pyrimidine; 3-(4-Chloro-2-pyrimidinyl)indole; 1146080-35-4; 3-(4-Chloro-pyrimidin-2-yl)-1H-indole
EINECS	Contact for details

Quality Control

Our 3-(4-Chloro-Pyrimidin-2-Yl)-1H-Indole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity confirmation and NMR for structural verification, to ensure it meets the specified 98+% purity standard. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.