Description

2,3-Dihydro-1H-Spiro[Isoquinoline-4,4'-Piperidine] is a high-purity, advanced pharmaceutical intermediate belonging to the spirocyclic amine class. This compound is a critical building block in modern medicinal chemistry, valued for its unique three-dimensional structure that enables the synthesis of novel bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of central nervous system (CNS) therapeutics and other small-molecule drug candidates. Our supply ensures consistent quality and reliable availability for your most demanding R&D and scale-up projects.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• CNS Drug Development: Particularly relevant for synthesizing potential therapeutics targeting neurological disorders.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses to introduce the spiro[isoquinoline-4,4'-piperidine] moiety.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting global drug discovery pipelines.
• Academic Research: Used in university and institutional labs for methodological development and biochemical research.

Basic Information

Item	Detail
Product Name	2,3-Dihydro-1H-Spiro[Isoquinoline-4,4'-Piperidine]
CAS No.	1145670-30-9
Molecular Formula	C13H16N2
Molecular Weight	200.28 g/mol
Synonyms	Spiro[isoquinoline-4,4'-piperidine], 2,3-Dihydro-1H-; 1'H-Spiro[piperidine-4,4'-isoquinoline]; 2,3-Dihydrospiro[isoquinoline-4,4'-piperidine]; 1'H-Spiro[isoquinoline-4,4'-piperidine]; 2,3-Dihydro-1H-spiro[isoquinoline-4,4'-piperidine]; Spirocyclic Amine Intermediate; CAS 1145670-30-9
EINECS	Contact for details

Quality Control

Every batch of 2,3-Dihydro-1H-Spiro[Isoquinoline-4,4'-Piperidine] is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with each shipment to guarantee traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.