Description

1-{[2-(Propan-2-Yl)Quinolin-4-Yl]Carbonyl}Piperidine-4-Carboxamide is a high-purity, advanced pharmaceutical intermediate belonging to the quinoline-carboxamide class of compounds. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel therapeutic agents with targeted biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new drugs, particularly in the areas of oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel small-molecule drug candidates for clinical research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new therapeutic entities.
• Oncology Drug Development: Employed in the research and development of potential kinase inhibitors and other targeted cancer therapies.
• CNS Drug Discovery: Acts as a scaffold for developing compounds targeting neurological pathways and receptors.
• Biochemical Research: Utilized as a reference standard or probe in biochemical assays to study protein-ligand interactions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects.

Basic Information

Product Name	1-{[2-(Propan-2-Yl)Quinolin-4-Yl]Carbonyl}Piperidine-4-Carboxamide
CAS No.	1144448-40-7
Molecular Formula	C19H23N3O2
Molecular Weight	325.41 g/mol
Synonyms	1-[(2-Isopropylquinolin-4-yl)carbonyl]piperidine-4-carboxamide; 4-Carbamoyl-1-[(2-isopropylquinoline-4-carbonyl)]piperidine; 1-{[2-(Propan-2-yl)quinolin-4-yl]carbonyl}piperidine-4-carboxylic acid amide; UNII-9G1JN6A8QN; 9G1JN6A8QN; 1144448-40-7; 1-[(2-Isopropyl-4-quinolyl)carbonyl]-4-piperidinecarboxamide; 1-{[2-(1-Methylethyl)-4-quinolinyl]carbonyl}-4-piperidinecarboxamide
EINECS	Contact for details

Quality Control

Our 1-{[2-(Propan-2-Yl)Quinolin-4-Yl]Carbonyl}Piperidine-4-Carboxamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality supports your research and development needs with reliable, traceable materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under inert atmosphere when appropriate for prolonged use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.